{"created":"2023-05-15T14:58:41.942135+00:00","id":16,"links":{},"metadata":{"_buckets":{"deposit":"b85a6e14-91ed-47c3-9724-0321155ef3f6"},"_deposit":{"created_by":10,"id":"16","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"16"},"status":"published"},"_oai":{"id":"oai:meiji-u.repo.nii.ac.jp:00000016","sets":["1:19","2:39"]},"author_link":["39","40","41","42","43"],"control_number":"16","item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The clinical effects of acupuncture in patients with mild cognitive impairment  ―Aβ sequence protein, as an index―","subitem_alternative_title_language":"en"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2018-03-16"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"明治国際医療大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"34318","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博 士（鍼灸学）","subitem_degreename_language":"ja"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2017年度","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】軽度認知障害を有する高齢者の認知機能低下に対する鍼治療の効果を，Aβシークエスタータンパク質を指標に比較試験の下で，その有効性を検討した．\n【対象】軽度認知障害を有する高齢者 17 名とした．脳トレーニングに加えて鍼治療を行う群 9 名（鍼治療群）と，脳トレーニングのみで経過観察を行う群 8 名（対照群）にブロックランダム割り付けした．\n【方法】鍼治療群は三焦鍼法をベースとした週 1 回の鍼治療を 3 ヶ月間，計 12 回行った．主要評価項目は MoCA-J スコア，副次評価項目は血清 Aβシークエスタータンパク質（TTR，ApoA1，C3），MPI スコア，HDL-C 値とした．\n【結果】主要評価項目では対照群と比べ，鍼治療群の MoCA-J スコア（Z=-2.153，r=0.52，p=0.031）は有意に増加した．副次評価項目では対照群と比べ，鍼治療群の ApoA1 値（Z=-2.168，r=0.53，p=0.030）が有意に増加した．対照群と比べ，鍼治療群の TTR 値（Z=-1.733，r=0.42，p=0.083）とHDL-C 値（Z=-1.498，r=0.36，p=0.134）は有意な増加は認められなかったが，効果量は「中」を示した．\n【考察】鍼治療は，MCI 高齢者の認知機能を改善させ，鍼治療による MCI の認知機能の改善に関しては，Aβシークエスタータンパク質の活性化が治効機序の一端とすることが示唆された．","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"34318鍼博甲第74号"}]},"item_10006_publisher_5":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"明治国際医療大学附属図書館"}]},"item_10006_relation_14":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"明治国際医療大学誌; 2017; 18: 9-15"}]}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"武岡, 崇介","creatorNameLang":"ja"},{"creatorName":"タケオカ, タカユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Takeoka, Takayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"39","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"江川, 雅人","creatorNameLang":"ja"},{"creatorName":"エガワ, マサト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"40","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"苗村, 建慈","creatorNameLang":"ja"},{"creatorName":"ナムラ, ケンジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"41","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Egawa, Masato","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"42","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Namura, Kenji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"43","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-24"}],"displaytype":"detail","filename":"02_takeoka18.pdf","filesize":[{"value":"661.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"02_takeoka18","objectType":"fulltext","url":"https://meiji-u.repo.nii.ac.jp/record/16/files/02_takeoka18.pdf"},"version_id":"e2c405ff-1260-47f3-8894-0f9fbcf926ed"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"鍼","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"認知機能","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"軽度認知障害","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Aβシーク エスタータンパク質","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"認知症予防","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"acupuncture","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cognitive function","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mild cognitive impairment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Aβ sequester protein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dementia prevention","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"軽度認知障害を有する高齢者の認知機能に対する鍼治療の効果 ―Aβシークエスタータンパク質を指標として―","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"軽度認知障害を有する高齢者の認知機能に対する鍼治療の効果 ―Aβシークエスタータンパク質を指標として―","subitem_title_language":"ja"}]},"item_type_id":"10006","owner":"10","path":["19","39"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-24"},"publish_date":"2022-02-24","publish_status":"0","recid":"16","relation_version_is_last":true,"title":["軽度認知障害を有する高齢者の認知機能に対する鍼治療の効果 ―Aβシークエスタータンパク質を指標として―"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-06-03T01:50:13.348015+00:00"}